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Enzymes are proteins that:

  1. Regulate metabolism

  2. Control gene expression

  3. Facilitate chemical reactions

  4. All of the above

The correct answer is: Facilitate chemical reactions

Enzymes are specialized proteins that act as catalysts in facilitating chemical reactions without being consumed in the process. While enzymes are involved in regulating metabolism, they do not directly control it. They also do not have a direct role in gene expression. Therefore, option A and B are incorrect. Option D is incorrect because enzymes do not have a role in regulating metabolism and controlling gene expression, making it a misleading option.